He has 30 years of experience in eHealth and connected health, medical imaging, biosignal analysis, intelligent systems and explainable AI, and more recently in mHealth interventions based on X Reality applications. He has been involved in numerous projects in these areas funded by EU and other bodies, with a total funding managed in excess of 20 million euros. He is the Technical Leader of the EU project funded under the Emergency Support Instrument Action for Cyprus to implement the EU Digital Covid Certificate Platform for the issuance of the corresponding certificates for vaccination, recovery and laboratory testing (eudcc.gov.cy which has been used by more than 1 million users). He is also leading the “Deployment of Generic Cross Border eHealth Services in Cyprus”, an EU Innovation and Networks Executive Agency (INEA), Connecting Europe Facility (CEF), funded project where 23-member states participate. He has published 152 journal publications, 268 conference papers, and 30 chapters in books in these areas (no. of citations more than 13500, h-score 56). He is a Member of the European Academy of Sciences and Arts, Fellow of IEEE, IET, International Academy of Medical and Biomedical Engineering (IAMBE) and European Alliance for Medical & Biological Engineering & Science (EAMBES).